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Ilan Schwartz
germhuntermd.bsky.social
did:plc:ifpfb7ltxahkp3g66s57jdqn
SUPERNOVA, an RCT of sipavibart vs evushield/placebo to prevent Covid in >3300 immunocompromised
Sipavibart assoc w fewer symptomatic Covid infxns at 6mo (NNT 29). No dif in severe dz (not powered for this). No efficacy vs Phe456Leu-containing variants eg XBB
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00804-1/fulltext
2025-02-25T13:28:05.977Z