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Seth Cheetham
sethcheetham.bsky.social
did:plc:4hotbgttdgwm6offka2rerc2
New #mRNA cap structures get you more bang (protein) for your buck! Nice new research from @jmcoller.bsky.social in collaboration with Trilink shows the CleanCap M6 analogue inhibits decapping and substantially increases protein expression in vivo.
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531%2825%2900010-1
2025-01-29T00:57:56.762Z